Malika Aid-Boudries, Ph.D.

Assistant Professor, HMS; CVVR group lead integrating multi-omics and AI to study host–virus interactions, vaccine responses, and disease pathogenesis.
Dr. Malika Aid Boudries, Ph.D., is an Assistant Professor in Medicine at Harvard Medical School, where she leverages cutting-edge omics technologies to advance the understanding of disease pathogenesis and immune responses to viral infections. With a strong foundation in bioinformatics from her doctoral training at Université de Montréal, Dr. Boudries has built a career at the intersection of computational biology, immunology, and virology.
Her expertise spans viral sequence variability, epigenetic profiling, vaccine immunology, and the integration of multi-omics data with artificial intelligence to uncover insights into complex biological systems.
Her research group develops and applies computational pipelines for multi-omics data integration—spanning transcriptomics, single-cell profiling, proteomics, and metabolomics—to interrogate host–virus interactions, define molecular correlates of vaccine responses, and elucidate mechanisms of disease pathogenesis. Her research has made significant contributions to the study of viral pathogens, including recent work on the immunopathogenesis of SARS-COV-2, HIV, MPOX and lethal H5N1 avian influenza virus infections. By combining multi-omics analysis with immunological studies, Dr. Boudries has helped illuminate the mechanisms driving severe disease outcomes, particularly the role of excessive inflammation, cytokine storms, and immune dysregulation. These findings not only deepen the scientific understanding of viral pathogenesis but also inform strategies for vaccine development and therapeutic interventions against emerging infectious diseases. Over the course of her career, Dr. Boudries has held research positions at leading institutions including the Montreal Clinical Research Institute, VGTI Florida, Case Western Reserve University, and the Center for Virology and Vaccine Research at Harvard. Beyond her research, she is dedicated to fostering scientific collaboration, mentoring early-career researchers, and advancing global health through innovation in virology, immunology, and computational biology. Her work exemplifies the power of interdisciplinary science in addressing some of the most pressing public health challenges of our time.
Away from the bench, she writes poetry. “I think of research as a poem: creative, purposeful, and meant to tell a story.”

• Université de Montréal – Ph.D
• Université de Montréal - MS in Bioinformatics
• Université Mouloud Mammeri de Tizi-Ouzou - MEng CS