Lorri Walters, BS, MBA
Lorri Walters, BS, MBA, is a seasoned Clinical Operations Leader with over 20 years of global experience advancing Phase I–IV clinical trials across therapeutic areas including obesity, diabetes, cardiovascular disease, oncology, infectious disease, and rare diseases. She has built a reputation for excellence in CRO/vendor oversight, regulatory strategy, GCP compliance, and leading cross-functional teams through FDA and EMA inspections. Lorri has contributed to high-impact programs supporting the approvals of Gardasil, Sogroya, and Wegovy, helping deliver therapies that generate billions in annual revenue and profoundly impact patient lives.
Beginning her career in pharmaceutical manufacturing, Lorri honed her leadership and operational skills as a chemist and manufacturing supervisor before transitioning into clinical research in 2004. Since then, she has steadily advanced through roles including Senior Clinical Research Associate, Trial Manager, and Senior Trial Manager, culminating in her current position as Global Clinical Trial Manager at Syneos Health. In this role, she oversees clinical operations across four continents and 15 countries, leading a team of 55 professionals while driving operational excellence, strategic planning, and innovative solutions in complex, matrixed environments.
Lorri’s leadership philosophy emphasizes growth, integrity, and collaboration. She is committed to building high-performing teams, mentoring talent, and fostering environments where people thrive. Beyond her professional achievements, she has served as Vice President of Membership for Toastmasters International and volunteered with Dress for Success, reflecting her dedication to empowering others. With a strong academic foundation in chemistry, business management, and nursing, Lorri continues to pursue opportunities to expand her strategic leadership capabilities, preparing for her next career milestone as Director of Clinical Operations.
• University of Phoenix - MBA
• Toastmasters
What do you attribute your success to?
I attribute my success to positive leadership, creating an environment where people want to work with you and for you. I love teaching and mentoring others; helping people grow is, to me, the hallmark of an effective leader. When you invest in others’ development, you build loyal followers and role models who elevate the whole team.
Although I’ve only been on staff for three months, I’ve already made a measurable impact; the Senior Director has reached out to me on several matters. That early recognition reinforces my belief that encouraging collaboration, celebrating wins, and making work enjoyable are essential leadership practices.
I intentionally make work fun because engagement fuels performance. When people enjoy their work and feel valued, they work harder and take pride in their results. Positive feedback and constructive coaching motivate people to improve and to bring their best to every project.
Leadership is about lifting others up, not tearing them down. Even when addressing challenges, I focus on what went well and how those strengths can be applied elsewhere. The way we speak to and treat one another matters, respectful, supportive communication creates the conditions for sustained success.
What’s the best career advice you’ve ever received?
The best career advice I’ve received is to seek coaches and mentors who lift you up rather than tear you down. Early in my job search I worked with two very different coaches: one who critiqued my resume harshly, yet I still had seven interviews scheduled, and another who praised my foundation and offered to help me make it even stronger without charging me. I gravitate toward the latter approach: coaches who recognize strengths and help you build on them.
This philosophy extends to leadership and everyday interactions. When leaders focus on elevating others and speaking with respect, teams become more confident, collaborative, and productive. Negativity never moves you forward; constructive encouragement does.
What advice would you give to young women entering your industry?
My best advice is to reach for the stars and actively seek out mentors in your field to learn and grow. I believe in putting myself forward, as a woman and a leader, I want my voice to be heard. I draw inspiration from women who rise to the top, including vice presidents and CEOs; their journeys remind me that rapid advancement is possible and worth pursuing.
When I was in my twenties I aspired to be a CEO in the pharmaceutical industry, and seeing women accelerate into leadership roles only strengthened that ambition. I hope my story will encourage others to think, I can do that too. Mentorship, innovation, and a positive mindset are powerful motivators that help us push boundaries and lift one another up.
What are the biggest challenges or opportunities in your field right now?
The biggest challenge right now is the widespread layoffs across pharmaceutical and clinical operations, which have left many talented professionals unemployed and made the job market far more competitive than it was eight to ten years ago.
Hiring processes have shifted dramatically, many organizations now rely on AI to screen resumes and conduct interviews, and traditional HR touchpoints are increasingly automated
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My strongest advice is to embrace AI as a tool, not a replacement. Learn platforms like Copilot, Gemini, and ChatGPT and use them to sharpen your communications and tailor your resume to specific job descriptions. I use AI daily to draft and refine emails and resumes; then I apply my judgment to improve the output. Treat AI as a partner that helps you optimize your materials and present your strengths more clearly.
Be persistent and adaptable. I revised my resume dozens of times to meet AI-driven scoring thresholds, and that effort paid off. Stay current with systems and tools, focus on measurable alignment with job requirements, and keep your skills and presentation on point. With the right mindset and tools, you can navigate this new landscape and remain competitive.
What values are most important to you in your work and personal life?
The values that guide me are positive leadership, teaching others, and making work enjoyable. I believe effective leaders inspire people to want to work with them and for them, and that mentoring is central to building strong teams. When leaders focus on strengths, celebrate progress, and create a fun, engaging environment, people take pride in their work and give their best effort.
I make a point of lifting others up in conversations, especially when someone is facing challenges, by highlighting what they did well and exploring how those strengths can be applied elsewhere.
The way we speak to and treat one another shapes team culture and performance.
I am also passionate about seeing more women step confidently into leadership roles. As a woman and a leader, I want my story to encourage others to aim high. When people read my article, I hope they feel inspired to say, I can do that too.
Locations
Syneos Health
Hatboro, PA 19040