Nina Graffe, Founder and CEO on Influential Women
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Influential Woman · Health Technology

Nina Graffe

Founder and CEO, ZAE (AEZAE Corp.)

Nashville, TN 37219

3Years experience

Certifications · Degrees · Memberships

Degree Instituto Universitario de Diseño Las Mercedes - B.Des.

Her Story

About Nina

Nina Graffe is a multidisciplinary entrepreneur, designer, and technology founder whose career bridges software architecture, wellness innovation, branding, and fine arts. Based in Nashville, Tennessee, she is the Founder and CEO of AEZAE Corp., where she leads the development of ZAE, a hormonal intelligence platform designed to help users understand and work with their bodies through state-adaptive biological insights.


With an academic background in fashion and apparel design, Nina transitioned from the creative arts into technology, combining design thinking, user experience, and human-centered innovation to address complex health challenges.


Driven by her own experiences with hormonal health and a desire to create better tools for future generations, Nina spent several years conceptualizing and building ZAE, a hormonal intelligence platform that serves five biological life-stages: women cycling, pregnant, postpartum, menopausal, and men on their own circadian rhythm. The platform leverages artificial intelligence and biological data to provide state-adaptive wellness guidance that responds to where a user's body actually is on any given day. Under her leadership, ZAE has introduced features such as AI-powered endocrine disruptor detection across food, beauty, household, and clothing categories; biological calendar synchronization; and adaptive wellness recommendations that reshape themselves around an individual's real-time physiological state.


Beyond her work in health technology, Nina is also an accomplished contemporary artist and entrepreneur with experience in fashion design, branding, and product development. Her creative philosophy centers on using technology as a medium for meaningful human connection, a principle reflected in both her artistic and business endeavors.


As an alumni graduated from the Spring 2026 TakeOff accelerator at the Nashville Entrepreneur Center, she has successfully guided ZAE from concept to market launch and continues to advocate for a biologically informed approach to wellness. Through innovation, creativity, and a strong sense of purpose, Nina is helping shape the future of health technology while empowering individuals to better understand and work with their own biology.

Her Interview

Ten minutes with Nina

01What do you attribute your success to?

I attribute it to my mother, and to the quiet way she taught me that limits are a choice.


She is a self-taught creator who can paint a canvas or build a dress out of nowhere. She has no formal training on those areas. She just decided, at some point, that she was capable, and then she was. I watched her do that for years before I understood what I was watching. I just absorbed the idea that you don't ask permission to be good at something. You just start, and you keep going, and one day you look up and you are.


That belief is what carried me from fashion design into fine art, and then from fine art into building a hormonal intelligence platform with no traditional engineering background. None of those transitions felt brave to me at the time. They felt obvious. Because she had already shown me what was possible.


Women leave imprints on other women, often without knowing it. My mother left hers on me. The least I can do is leave one for someone else.

02What’s the best career advice you’ve ever received?

The honest answer is that the most useful guidance I've received wasn't career advice at all. It came from watching my mother create things without ever asking whether she was qualified to create them.


The lesson is this: the ability to achieve a goal is not something someone grants you. It is your decision. It all depends on you and on how much you trust yourself. The people moving fastest are the ones who decided the rules don't apply to them.


So, I stopped asking for permission to learn what I needed to learn. I stopped waiting for a credential to validate what I could already do. And every time someone told me, "You can't do that without [the right background, the right credential, the right funding]," that simply gave me the fuel to show them that 'Yes, I can.'


That has done more for my career than any single piece of professional advice ever could.

03What advice would you give to young women entering your industry?

Believe in yourself before you ask anyone else to believe in you.


If you have an idea, it exists because you have the internal capacity to build it. The world is full of people who will doubt you politely, and a smaller number who will doubt you out loud. Both groups are wrong, and neither of them is in the room when you sit down to do the work.


I built a hormonal intelligence platform with a background in art and fashion design. I had no traditional engineering credentials. I did it anyway, because I realized that if I didn't build it, no one was going to. The people whose bodies this platform serves were not going to wait for someone with a "more appropriate" résumé to show up.


Caring is not a soft skill. It is the rarest skill, and it is the one thing that turns technology into something that actually helps a human being. If you care enough about a problem to lose sleep over it, you are already qualified to solve it.


So don't ask whether you fit. Build the thing, and the fit will reveal itself.


If you're a woman reading this and wondering if you belong in this industry: yes. You do. If you have the vision, if you can see what needs to be built, you're already the right person to build it. Just start.

04What are the biggest challenges or opportunities in your field right now?

The biggest challenge is that the wellness industry is not only fragmented, but it is also biologically blind. It has spent a decade giving millions of users the same generic advice on Monday that it gives them on Friday.


But everyone's biology is different, and the body isn't the same on Monday as it is on Friday. A woman in her follicular phase doesn't need what a woman in her luteal phase needs. A pregnant body doesn't need what a postpartum body needs. A woman in menopause doesn't need what a 24-year-old needs. And men, actually have their own circadian rhythm that almost no consumer app takes into consideration.


Five biological life-stages. Most apps serve one and call it "women's health."


That gap is the opportunity. The next generation of wellness technology will solve the data fragmentation users are drowning in, and most importantly, it will know what day it is for your body, not just what day it is on your calendar. It will adjust the entire experience around your actual state, in real time. That's what we've built at ZAE.


The future of wellness isn't another app. It is infrastructure. ZAE is that infrastructure.

05What values are most important to you in your work and personal life?

Three things anchor everything I do: depth, honesty, and connection.


Depth, because anything worth building requires going further than seems reasonable. The industry tells everyone to "ship fast and break things." I refused to. I spent two years conceptualizing, and eight months building, because I refused to ship a product that wasn't at the level that the people who would use it deserve.


Honesty, because being honest with others, but especially with yourself, is the bravest thing you can do. Honesty makes you aware of your weaknesses, of what's lacking in your life, of what you need to improve so you can become the person you are meant to be.


And connection, because connection is what gives meaning to anything you do. The same thread runs through my art and my technology. A painting and a piece of software both ask the same questions:


Is this truly meaningful? Did this make someone feel seen? Can you truly connect with it?


Whatever I build next, on a canvas, in code, in conversation, I want it to be something that people can connect with. Something that helps someone feel a little more understood by this world we are moving through.

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